Category: Insulin

The physiology and biochemistry of the Paleolithic Diet AHS 13 with markingsDear Reader,

I just gave a talk at the Ancestral Health Symposium on the potential role of transient receptor potential vanilloid 1 in obesity. Here’s the entire video for you to watch! Watch out for the sing a long at the end, though, you might be singing alone at your desk!


Insulin resistance is the bane of the excess carbohydrate diet!

When excess carbohydrates are chronically ingested, the insulin receptors in the brain lose their ability to mediate the anorexigenic signal properly! this is the essence of insulin resistance. Thus, your brain does not get a good signal to stop eating!

The result is catastrophic! Because the anorexigenic signal is not encoded properly, you eat more. And if you eat more carbohydrates, well, then you make more insulin which causes a further increase in insulin resistance! Thus the signal to stop eating is lost! Thus you eat more. This cycle is only going to stop when carbohydrate intake is reduced.